Authors: Abd-Alaziz A
The aim of the current study was to retrospectively compare the maternal and neonatal outcomes of delivery in women with preterm prelabor rupture of the membranes (PPROM) who deliver before and after 34 weeks of gestation over a period of three years in Ain Shams University Maternity Hospital.This retrospective study included singleton pregnant women with a diagnosis of PPROM. Only women who were eligible for expectant management for at least 48 hours were included in the analysis. Neonatal outcomes included admission to neonatal intensive care unit (NICU) for neonatal sepsis or respiratory distress, neonatal jaundice, and perinatal mortality. Maternal outcomes included fever, chorioamnionitis, umbilical cord prolapse, and postpartum pyrexia.A total of 1721 eligible women were included in the final analysis. The mean age of included women was 24.22 ± 4.5 years (range: 18 – 38 years). The mean gestational age at delivery was 33.17 ± 3.8 weeks (range: 28.14 – 36 weeks). The included women were divided into 2 groups: group I (n=953) including women who delivered at < 34 weeks of gestation; and group II (n=768) including women who delivered at ≥ 34 weeks of gestation. The rate of chorioamnionitis was significantly higher in women of group II [39 (5.1%) vs. 28 (2.9%), respectively, p=0.023].The rate of NICU admission for neonatal sepsis was significantly higher in women of group II [49 (6.4%) vs. 37 (3.9%)), respectively, p=0.018].
Prelabor rupture of the membranes – Chorioamnionitis – neonatal respiratory distress syndrome
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