Authors: Sweed M.(MD)


To evaluate the tubal patency after methotrexate therapy compared to linear salpingostomy using saline infusion sonohysterography. It was a case-series study that was done at Ain Shams University Maternity Hospital (ASMUH) and included women who were admitted for having tubal pregnancy and treated by a single modality either methotrexate (MTX) or linear salpingostomy, over a 5-year period, between January 2010 and December 2014.  300 patients were recruited and divided into two equal arms 150 women in each.  Group I were treated by methotrexate either single dose or multiple doses, while group II included women who underwent conservative surgical management (linear salpingostomy) either through laparoscopy or laparotomy. Saline infusion sonohysterography was performed for all participants and tubal patency was assessed in all women.  Data was gathered from patient records present at “Patient Records Department” at ASUMH. There was no statistically significant difference between the two groups as regards to the tubal patency either on affected side or contralateral side.  However, patients had multiple doses of methotrexate had less tubal patency rates than those who treated by a single dose therapy.  The approach of linear salpingo(s)tomy did not show a significant difference in tubal patency.  



Tubal pregnancy; Methotrexate; Salpingostomy; Saline infusion sonohysterography

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Saline Infusion Sonohysterography for Assessment of Tubal Patency after Methotrexate Therapy versus Linear Salpingostomy