Pregnancy outcome in Peripartum Cardiomyopathy

Authors: Anuja Bhalerao , Richa Garg

Abstract

Peripartum cardiomyopathy is a rare disease affecting women of reproductive age. Incidence of peripartum cardiomyopathy is less than 0.1% and has maternal morbidity and mortality rate of 5% to 32%. The aim of our study was, to study the clinical profile, prognostic factors, and the management along with obstetric outcome, in women with peripartum cardiomyopathy. This prospective hospital based observational study was carried out over 3 years at a rural tertiary care center. Antenatal women in reproductive age group of 20 years to 40 years attending the labour ward of a tertiary care center, presenting with peripartum cardiomyopathy, were included. Multiparas constituted 81% (9/11). Two cases (18.18%) developed persistent cardiomyopathy (persistent left ventricular dysfunction beyond six months of presentation). 4/11 (36.36%) women recovered clinically (those who became symptomatically better, breathless-ness decreased, chest became clear) whereas the LV function recovered (ejection fraction increased) in 3 women (27.27%). Two women had thromboembolism and required thromboprophylaxis. Maternal mortality was 27.27% (3/11). 6/11 babies were small for date. There were 2 intrauterine deaths, and 1 neonatal death. 4/11(36.36%) women underwent cesarean section for foetal distress.

 

Keywords

Peripartum cardiomyopathy, maternal outcome, fetal outcome, Echocardiography, cardiovascular disease

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Pregnancy outcome in Peripartum Cardiomyopathy